Volume 5, Issue 2
Nano-Yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering

Jun Li, Wei Liu, Anlin Yin, Jinglei Wu, Salem S. Al-Deyab, Mohamed El-Newehy & Xiumei Mo

Journal of Fiber Bioengineering & Informatics, 5 (2012), pp. 169-179.

Published online: 2012-05

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  • Abstract

In this paper, novel nano-yarn reinforced scaffolds were fabricated and further biomineralized by submerging in 10 × Simulated Body Fluid (SBF). The compressive strength of P(LLA-CL)/Silk Fibroin (SF) nano-yarns reinforced scaffold was 1.72 ± 0.50 MPa and its porosity is 82.8%. Fourier Transform Infrared Spectrum (FTIR) and X-ray Diffraction (XRD) data confirmed the mineral phase was made of Hydroxyapatite (HA). MC3T3-E1 cell proliferation and differentiation on the scaffolds were evaluated. In vitro biological evaluation showed that HA coated scaffolds provided higher cell proliferation efficiency (t-test, P › 0:05) than uncoated scaffolds.

  • Keywords

Nanofibres Wound Dressing Drug Delivery

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COPYRIGHT: © Global Science Press

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@Article{JFBI-5-169, author = {}, title = {Nano-Yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering}, journal = {Journal of Fiber Bioengineering and Informatics}, year = {2012}, volume = {5}, number = {2}, pages = {169--179}, abstract = {In this paper, novel nano-yarn reinforced scaffolds were fabricated and further biomineralized by submerging in 10 × Simulated Body Fluid (SBF). The compressive strength of P(LLA-CL)/Silk Fibroin (SF) nano-yarns reinforced scaffold was 1.72 ± 0.50 MPa and its porosity is 82.8%. Fourier Transform Infrared Spectrum (FTIR) and X-ray Diffraction (XRD) data confirmed the mineral phase was made of Hydroxyapatite (HA). MC3T3-E1 cell proliferation and differentiation on the scaffolds were evaluated. In vitro biological evaluation showed that HA coated scaffolds provided higher cell proliferation efficiency (t-test, P › 0:05) than uncoated scaffolds.}, issn = {2617-8699}, doi = {https://doi.org/10.3993/jfbi06201206}, url = {http://global-sci.org/intro/article_detail/jfbi/4872.html} }
TY - JOUR T1 - Nano-Yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering JO - Journal of Fiber Bioengineering and Informatics VL - 2 SP - 169 EP - 179 PY - 2012 DA - 2012/05 SN - 5 DO - http://doi.org/10.3993/jfbi06201206 UR - https://global-sci.org/intro/article_detail/jfbi/4872.html KW - Nanofibres KW - Wound Dressing KW - Drug Delivery AB - In this paper, novel nano-yarn reinforced scaffolds were fabricated and further biomineralized by submerging in 10 × Simulated Body Fluid (SBF). The compressive strength of P(LLA-CL)/Silk Fibroin (SF) nano-yarns reinforced scaffold was 1.72 ± 0.50 MPa and its porosity is 82.8%. Fourier Transform Infrared Spectrum (FTIR) and X-ray Diffraction (XRD) data confirmed the mineral phase was made of Hydroxyapatite (HA). MC3T3-E1 cell proliferation and differentiation on the scaffolds were evaluated. In vitro biological evaluation showed that HA coated scaffolds provided higher cell proliferation efficiency (t-test, P › 0:05) than uncoated scaffolds.
Jun Li, Wei Liu, Anlin Yin, Jinglei Wu, Salem S. Al-Deyab, Mohamed El-Newehy & Xiumei Mo. (2019). Nano-Yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering. Journal of Fiber Bioengineering and Informatics. 5 (2). 169-179. doi:10.3993/jfbi06201206
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