TY - JOUR
T1 - Nano-Yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering
AU - Jun Li, Wei Liu, Anlin Yin, Jinglei Wu, Salem S. Al-Deyab, Mohamed El-Newehy & Xiumei Mo
JO - Journal of Fiber Bioengineering and Informatics
VL - 2
SP - 169
EP - 179
PY - 2012
DA - 2012/05
SN - 5
DO - http://doi.org/10.3993/jfbi06201206
UR - https://global-sci.org/intro/article_detail/jfbi/4872.html
KW - Nanofibres
KW - Wound Dressing
KW - Drug Delivery
AB - In this paper, novel nano-yarn reinforced scaffolds were fabricated and further biomineralized by
submerging in 10 × Simulated Body Fluid (SBF). The compressive strength of P(LLA-CL)/Silk Fibroin
(SF) nano-yarns reinforced scaffold was 1.72 ± 0.50 MPa and its porosity is 82.8%. Fourier Transform
Infrared Spectrum (FTIR) and X-ray Diffraction (XRD) data confirmed the mineral phase was made of
Hydroxyapatite (HA). MC3T3-E1 cell proliferation and differentiation on the scaffolds were evaluated.
In vitro biological evaluation showed that HA coated scaffolds provided higher cell proliferation efficiency
(t-test, P › 0:05) than uncoated scaffolds.