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Volume 7, Issue 2
The Characteristics of Self-assembled Tussah Silk Fibroin Nanoparticles for Controlled Drug Release

Jinjing Chen, Hongqin Yu & Jianxin He

Journal of Fiber Bioengineering & Informatics, 7 (2014), pp. 189-197.

Published online: 2014-07

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  • Abstract
Tussah silk fibroin is a promising material for drug release because of protein component, biocompatibility, aqueous processability, and biodegradability. Tussah silk fibroin nanoparticles were self-assembled and prepared in this paper. Their appearances and sizes were modified by altering the volume ratios between tussah silk fibroin and ethanol. When 9 mL of ethanol was added, the average microsphere size was 184.52 nm and the scattered index was 0.2903. The tussah silk fibroin nanoparticles for controlled drug release was studied and the result showed that the time of drug release was significantly longer. The process of drug release was divided into rapid release in early stage and slow release in late stage. The target drug delivery can reduce the negative effects and improve the efficiency of the drug. As a result, it favors deeper investigation of tussah silk fibroin nanoparticles as drug carriers for controlled release of sensitive biologicals.
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@Article{JFBI-7-189, author = {}, title = {The Characteristics of Self-assembled Tussah Silk Fibroin Nanoparticles for Controlled Drug Release}, journal = {Journal of Fiber Bioengineering and Informatics}, year = {2014}, volume = {7}, number = {2}, pages = {189--197}, abstract = {Tussah silk fibroin is a promising material for drug release because of protein component, biocompatibility, aqueous processability, and biodegradability. Tussah silk fibroin nanoparticles were self-assembled and prepared in this paper. Their appearances and sizes were modified by altering the volume ratios between tussah silk fibroin and ethanol. When 9 mL of ethanol was added, the average microsphere size was 184.52 nm and the scattered index was 0.2903. The tussah silk fibroin nanoparticles for controlled drug release was studied and the result showed that the time of drug release was significantly longer. The process of drug release was divided into rapid release in early stage and slow release in late stage. The target drug delivery can reduce the negative effects and improve the efficiency of the drug. As a result, it favors deeper investigation of tussah silk fibroin nanoparticles as drug carriers for controlled release of sensitive biologicals.}, issn = {2617-8699}, doi = {https://doi.org/10.3993/jfbi06201406}, url = {http://global-sci.org/intro/article_detail/jfbi/4777.html} }
TY - JOUR T1 - The Characteristics of Self-assembled Tussah Silk Fibroin Nanoparticles for Controlled Drug Release JO - Journal of Fiber Bioengineering and Informatics VL - 2 SP - 189 EP - 197 PY - 2014 DA - 2014/07 SN - 7 DO - http://doi.org/10.3993/jfbi06201406 UR - https://global-sci.org/intro/article_detail/jfbi/4777.html KW - Tussah Silk Fibroin KW - Nanoparticle KW - Drug Release KW - Self-assembly AB - Tussah silk fibroin is a promising material for drug release because of protein component, biocompatibility, aqueous processability, and biodegradability. Tussah silk fibroin nanoparticles were self-assembled and prepared in this paper. Their appearances and sizes were modified by altering the volume ratios between tussah silk fibroin and ethanol. When 9 mL of ethanol was added, the average microsphere size was 184.52 nm and the scattered index was 0.2903. The tussah silk fibroin nanoparticles for controlled drug release was studied and the result showed that the time of drug release was significantly longer. The process of drug release was divided into rapid release in early stage and slow release in late stage. The target drug delivery can reduce the negative effects and improve the efficiency of the drug. As a result, it favors deeper investigation of tussah silk fibroin nanoparticles as drug carriers for controlled release of sensitive biologicals.
Jinjing Chen, Hongqin Yu & Jianxin He. (2019). The Characteristics of Self-assembled Tussah Silk Fibroin Nanoparticles for Controlled Drug Release. Journal of Fiber Bioengineering and Informatics. 7 (2). 189-197. doi:10.3993/jfbi06201406
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