Volume 6, Issue 3
Electrospun Nanofibers for Tissue Engineering

Xiumei Mo, Dawei Li, Hany A. EI-Hamshary & Salem S. Al-Deyab

Journal of Fiber Bioengineering & Informatics, 6 (2013), pp. 225-235.

Published online: 2013-06

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  • Abstract

Electrospun nanofibers have increasingly attracted attention to be used as new generation tissue engineering scaffolds since they have the nanofibrous structure, which can biomimic the native Extracellular Matrix (ECM). This paper gives the review of our 10 years research on electrospun nanofibers for tissue engineering. Natural polymers like collagen and chitosan have been electrospun into complex nanofibers to biomimic the native ECM both in structure and components. Collagen-chitosan or silk fibroin (SF) was also blended with synthetic poly (L-lactide-co-ε-caprolactone) (P(LLA-CL)) and electrospun into collgen-chitosan-P (LLA-CL) nanofibers or SF-P(LLA-CL) nanofibers to achieve both good mechanical properties and biocompatibility. Coaxial electrospinning was used to encapsulate the biomolecules into nanofibers to display antithrombotic properties. The nanofiber scaffolds have been used for skin, nerve and blood vessel tissue engineering in vivo.

  • Keywords

Nanofiber Electrospinning Tissue Engineering P (LLA-CL) Scaffolds

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COPYRIGHT: © Global Science Press

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@Article{JFBI-6-225, author = {}, title = {Electrospun Nanofibers for Tissue Engineering}, journal = {Journal of Fiber Bioengineering and Informatics}, year = {2013}, volume = {6}, number = {3}, pages = {225--235}, abstract = {Electrospun nanofibers have increasingly attracted attention to be used as new generation tissue engineering scaffolds since they have the nanofibrous structure, which can biomimic the native Extracellular Matrix (ECM). This paper gives the review of our 10 years research on electrospun nanofibers for tissue engineering. Natural polymers like collagen and chitosan have been electrospun into complex nanofibers to biomimic the native ECM both in structure and components. Collagen-chitosan or silk fibroin (SF) was also blended with synthetic poly (L-lactide-co-ε-caprolactone) (P(LLA-CL)) and electrospun into collgen-chitosan-P (LLA-CL) nanofibers or SF-P(LLA-CL) nanofibers to achieve both good mechanical properties and biocompatibility. Coaxial electrospinning was used to encapsulate the biomolecules into nanofibers to display antithrombotic properties. The nanofiber scaffolds have been used for skin, nerve and blood vessel tissue engineering in vivo.}, issn = {2617-8699}, doi = {https://doi.org/10.3993/jfbi09201301}, url = {http://global-sci.org/intro/article_detail/jfbi/4837.html} }
TY - JOUR T1 - Electrospun Nanofibers for Tissue Engineering JO - Journal of Fiber Bioengineering and Informatics VL - 3 SP - 225 EP - 235 PY - 2013 DA - 2013/06 SN - 6 DO - http://doi.org/10.3993/jfbi09201301 UR - https://global-sci.org/intro/article_detail/jfbi/4837.html KW - Nanofiber KW - Electrospinning KW - Tissue Engineering KW - P (LLA-CL) KW - Scaffolds AB - Electrospun nanofibers have increasingly attracted attention to be used as new generation tissue engineering scaffolds since they have the nanofibrous structure, which can biomimic the native Extracellular Matrix (ECM). This paper gives the review of our 10 years research on electrospun nanofibers for tissue engineering. Natural polymers like collagen and chitosan have been electrospun into complex nanofibers to biomimic the native ECM both in structure and components. Collagen-chitosan or silk fibroin (SF) was also blended with synthetic poly (L-lactide-co-ε-caprolactone) (P(LLA-CL)) and electrospun into collgen-chitosan-P (LLA-CL) nanofibers or SF-P(LLA-CL) nanofibers to achieve both good mechanical properties and biocompatibility. Coaxial electrospinning was used to encapsulate the biomolecules into nanofibers to display antithrombotic properties. The nanofiber scaffolds have been used for skin, nerve and blood vessel tissue engineering in vivo.
Xiumei Mo, Dawei Li, Hany A. EI-Hamshary & Salem S. Al-Deyab. (2019). Electrospun Nanofibers for Tissue Engineering. Journal of Fiber Bioengineering and Informatics. 6 (3). 225-235. doi:10.3993/jfbi09201301
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