Volume 11, Issue 4
Preparation and Characterization of the Silk Fibroin 3D Scaffolds with Porous and Interconnected Structure

Jun Song, Xiaoqin WangJiashen Li

Journal of Fiber Bioengineering & Informatics, 11 (2018), pp. 183-195.

Published online: 2019-02

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  • Abstract

Silk fibroin (SF) is wildly used in the field of biomedical science. Considering the contradiction between suitable pore size and outstanding mechanical properties, this research focused on the topic of preparing the 3D scaffolds with large pore sizes and high interconnectivity. For preparing the silk fibroin 3D scaffold samples, three kinds of porogens were applied in two methods which paraffin spheres were used in freezedrying. Sodium chloride (NaCl) and sodium carbonate (Na2CO3) were used in leaching respectively. Different pore size of porogens were used to control the pore size and porosities of prepared scaffold samples. Some basic properties of scaffold samples were characterized including surface morphology, chemical structure, porosity and mechanical performance. The best porosity of sample reached to 93% in the research.

  • Keywords

Silk fibroin Paraffin spheres Tissue engineering Porous scaffold.

  • AMS Subject Headings

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COPYRIGHT: © Global Science Press

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@Article{JFBI-11-183, author = {Song , Jun and Wang , Xiaoqin and Li , Jiashen}, title = {Preparation and Characterization of the Silk Fibroin 3D Scaffolds with Porous and Interconnected Structure}, journal = {Journal of Fiber Bioengineering and Informatics}, year = {2019}, volume = {11}, number = {4}, pages = {183--195}, abstract = {

Silk fibroin (SF) is wildly used in the field of biomedical science. Considering the contradiction between suitable pore size and outstanding mechanical properties, this research focused on the topic of preparing the 3D scaffolds with large pore sizes and high interconnectivity. For preparing the silk fibroin 3D scaffold samples, three kinds of porogens were applied in two methods which paraffin spheres were used in freezedrying. Sodium chloride (NaCl) and sodium carbonate (Na2CO3) were used in leaching respectively. Different pore size of porogens were used to control the pore size and porosities of prepared scaffold samples. Some basic properties of scaffold samples were characterized including surface morphology, chemical structure, porosity and mechanical performance. The best porosity of sample reached to 93% in the research.

}, issn = {2617-8699}, doi = {https://doi.org/10.3993/jfbim00288}, url = {http://global-sci.org/intro/article_detail/jfbi/13008.html} }
TY - JOUR T1 - Preparation and Characterization of the Silk Fibroin 3D Scaffolds with Porous and Interconnected Structure AU - Song , Jun AU - Wang , Xiaoqin AU - Li , Jiashen JO - Journal of Fiber Bioengineering and Informatics VL - 4 SP - 183 EP - 195 PY - 2019 DA - 2019/02 SN - 11 DO - http://doi.org/10.3993/jfbim00288 UR - https://global-sci.org/intro/article_detail/jfbi/13008.html KW - Silk fibroin KW - Paraffin spheres KW - Tissue engineering KW - Porous scaffold. AB -

Silk fibroin (SF) is wildly used in the field of biomedical science. Considering the contradiction between suitable pore size and outstanding mechanical properties, this research focused on the topic of preparing the 3D scaffolds with large pore sizes and high interconnectivity. For preparing the silk fibroin 3D scaffold samples, three kinds of porogens were applied in two methods which paraffin spheres were used in freezedrying. Sodium chloride (NaCl) and sodium carbonate (Na2CO3) were used in leaching respectively. Different pore size of porogens were used to control the pore size and porosities of prepared scaffold samples. Some basic properties of scaffold samples were characterized including surface morphology, chemical structure, porosity and mechanical performance. The best porosity of sample reached to 93% in the research.

Jun Song, Xiaoqin Wang & Jiashen Li. (2020). Preparation and Characterization of the Silk Fibroin 3D Scaffolds with Porous and Interconnected Structure. Journal of Fiber Bioengineering and Informatics. 11 (4). 183-195. doi:10.3993/jfbim00288
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