Novel Atmospheric Plasma Enhanced Silk Fibroin Nanofiber/Gauze Composite Wound Dressings
DOI:
10.3993/jfbi09201201
Journal of Fiber Bioengineering & Informatics, 5 (2012), pp. 227-242.
Published online: 2012-05
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@Article{JFBI-5-227,
author = {Rupesh Nawalakhe, Quan Shi, Narendiran Vitchuli, Mohamed A. Bourham, Xiangwu Zhang and Marian G. McCord},
title = {Novel Atmospheric Plasma Enhanced Silk Fibroin Nanofiber/Gauze Composite Wound Dressings},
journal = {Journal of Fiber Bioengineering and Informatics},
year = {2012},
volume = {5},
number = {3},
pages = {227--242},
abstract = {In this work, Silk Fibroin (SF) nanofibers were electrospun onto plasma-treated 100% cotton gauze
bandages to form a novel silk-gauze composite wound dressing. Atmospheric pressure plasma pre- and
post-treatments were used to increase the adhesion between the SF nanofibers and cotton substrates.
The adhesion of the nanofibers to the substrates was assessed by qualitative and quantitative techniques.
Plasma pre-treatment of the substrate with 100% helium and 99% helium/1% oxygen plasmas showed up
to a 50% increase in the force required to peel off the nanofiber layer. This force was further increased up
to 75% after pre- as well as post-plasma treatment of the composite bandages. Plasma pre-treatment of
the gauze fabric prior to nanofiber deposition and post-treatment to the composite bandages significantly
reduced degradation of the nanofiber layer during repetitive flexing. Air permeability and moisture vapor
transport were significantly reduced due to the presence of a nanofiber layer upon the substrate. The
results of surface elemental analysis showed that the adhesion and durability increase are mainly due to
the active species generated by plasma on the surface of cotton substrate as well as on the surface of the
silk fibroin nanofibers.},
issn = {2617-8699},
doi = {https://doi.org/10.3993/jfbi09201201},
url = {http://global-sci.org/intro/article_detail/jfbi/4877.html}
}
TY - JOUR
T1 - Novel Atmospheric Plasma Enhanced Silk Fibroin Nanofiber/Gauze Composite Wound Dressings
AU - Rupesh Nawalakhe, Quan Shi, Narendiran Vitchuli, Mohamed A. Bourham, Xiangwu Zhang & Marian G. McCord
JO - Journal of Fiber Bioengineering and Informatics
VL - 3
SP - 227
EP - 242
PY - 2012
DA - 2012/05
SN - 5
DO - http://doi.org/10.3993/jfbi09201201
UR - https://global-sci.org/intro/article_detail/jfbi/4877.html
KW - Wound Healing
KW - Adhesion
KW - Silk Fibroin
KW - Nanofibers
KW - Wound Dressings
KW - Bandages
KW - Atmospheric Pressure Plasma
AB - In this work, Silk Fibroin (SF) nanofibers were electrospun onto plasma-treated 100% cotton gauze
bandages to form a novel silk-gauze composite wound dressing. Atmospheric pressure plasma pre- and
post-treatments were used to increase the adhesion between the SF nanofibers and cotton substrates.
The adhesion of the nanofibers to the substrates was assessed by qualitative and quantitative techniques.
Plasma pre-treatment of the substrate with 100% helium and 99% helium/1% oxygen plasmas showed up
to a 50% increase in the force required to peel off the nanofiber layer. This force was further increased up
to 75% after pre- as well as post-plasma treatment of the composite bandages. Plasma pre-treatment of
the gauze fabric prior to nanofiber deposition and post-treatment to the composite bandages significantly
reduced degradation of the nanofiber layer during repetitive flexing. Air permeability and moisture vapor
transport were significantly reduced due to the presence of a nanofiber layer upon the substrate. The
results of surface elemental analysis showed that the adhesion and durability increase are mainly due to
the active species generated by plasma on the surface of cotton substrate as well as on the surface of the
silk fibroin nanofibers.
Rupesh Nawalakhe, Quan Shi, Narendiran Vitchuli, Mohamed A. Bourham, Xiangwu Zhang and Marian G. McCord. (2012). Novel Atmospheric Plasma Enhanced Silk Fibroin Nanofiber/Gauze Composite Wound Dressings.
Journal of Fiber Bioengineering and Informatics. 5 (3).
227-242.
doi:10.3993/jfbi09201201
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