Volume 6, Issue 1
Bio-inspired Electrospun Fibre Structures - Numerical Model

Budimir Mijovic & Ante Agic

Journal of Fiber Bioengineering & Informatics, 6 (2013), pp. 23-32.

Published online: 2013-06

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  • Abstract

A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly(ε-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical scaffold could be more beneficial for tissue engineering applications than for individual scaffolds.

  • Keywords

Electrospun PCL Multiscale Numerical Model

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COPYRIGHT: © Global Science Press

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@Article{JFBI-6-23, author = {}, title = {Bio-inspired Electrospun Fibre Structures - Numerical Model}, journal = {Journal of Fiber Bioengineering and Informatics}, year = {2013}, volume = {6}, number = {1}, pages = {23--32}, abstract = {A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly(ε-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical scaffold could be more beneficial for tissue engineering applications than for individual scaffolds.}, issn = {2617-8699}, doi = {https://doi.org/10.3993/jfbi03201302}, url = {http://global-sci.org/intro/article_detail/jfbi/4818.html} }
TY - JOUR T1 - Bio-inspired Electrospun Fibre Structures - Numerical Model JO - Journal of Fiber Bioengineering and Informatics VL - 1 SP - 23 EP - 32 PY - 2013 DA - 2013/06 SN - 6 DO - http://dor.org/10.3993/jfbi03201302 UR - https://global-sci.org/intro/article_detail/jfbi/4818.html KW - Electrospun PCL KW - Multiscale KW - Numerical Model AB - A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly(ε-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical scaffold could be more beneficial for tissue engineering applications than for individual scaffolds.
Budimir Mijovic & Ante Agic. (2019). Bio-inspired Electrospun Fibre Structures - Numerical Model. Journal of Fiber Bioengineering and Informatics. 6 (1). 23-32. doi:10.3993/jfbi03201302
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