Volume 7, Issue 4
Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary

Shihai Zhao & Tsorng-Whay Pan

Numer. Math. Theor. Meth. Appl., 7 (2014), pp. 499-511.

Published online: 2014-07

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  • Abstract

Computational modeling and simulation are presented on the motion of red blood cells behind a moving interface in a capillary. The methodology is based on an immersed boundary method and the skeleton structure of the red blood cell (RBC) membrane is modeled as a spring network.  As by the nature of the problem, the computational domain is moving with either a designated RBC or an interface in an infinitely long two-dimensional channel with an undisturbed flow field in front of the computational domain. The tanking-treading and the inclination angle of a cell in a simple shear flow are briefly discussed for the validation purpose. We then present and discuss the results of the motion of red blood cells behind a moving interface in a capillary, which show that the RBCs with higher velocity than the interface speed form a concentrated slug behind the moving interface.

  • Keywords

Red blood cells, moving domain, immersed boundary method.

  • AMS Subject Headings

65M60, 76M10, 76Z05

  • Copyright

COPYRIGHT: © Global Science Press

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@Article{NMTMA-7-499, author = {}, title = {Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary}, journal = {Numerical Mathematics: Theory, Methods and Applications}, year = {2014}, volume = {7}, number = {4}, pages = {499--511}, abstract = {

Computational modeling and simulation are presented on the motion of red blood cells behind a moving interface in a capillary. The methodology is based on an immersed boundary method and the skeleton structure of the red blood cell (RBC) membrane is modeled as a spring network.  As by the nature of the problem, the computational domain is moving with either a designated RBC or an interface in an infinitely long two-dimensional channel with an undisturbed flow field in front of the computational domain. The tanking-treading and the inclination angle of a cell in a simple shear flow are briefly discussed for the validation purpose. We then present and discuss the results of the motion of red blood cells behind a moving interface in a capillary, which show that the RBCs with higher velocity than the interface speed form a concentrated slug behind the moving interface.

}, issn = {2079-7338}, doi = {https://doi.org/10.4208/nmtma.2014.1301si}, url = {http://global-sci.org/intro/article_detail/nmtma/5886.html} }
TY - JOUR T1 - Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary JO - Numerical Mathematics: Theory, Methods and Applications VL - 4 SP - 499 EP - 511 PY - 2014 DA - 2014/07 SN - 7 DO - http://doi.org/10.4208/nmtma.2014.1301si UR - https://global-sci.org/intro/article_detail/nmtma/5886.html KW - Red blood cells, moving domain, immersed boundary method. AB -

Computational modeling and simulation are presented on the motion of red blood cells behind a moving interface in a capillary. The methodology is based on an immersed boundary method and the skeleton structure of the red blood cell (RBC) membrane is modeled as a spring network.  As by the nature of the problem, the computational domain is moving with either a designated RBC or an interface in an infinitely long two-dimensional channel with an undisturbed flow field in front of the computational domain. The tanking-treading and the inclination angle of a cell in a simple shear flow are briefly discussed for the validation purpose. We then present and discuss the results of the motion of red blood cells behind a moving interface in a capillary, which show that the RBCs with higher velocity than the interface speed form a concentrated slug behind the moving interface.

Shihai Zhao & Tsorng-Whay Pan. (2020). Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary. Numerical Mathematics: Theory, Methods and Applications. 7 (4). 499-511. doi:10.4208/nmtma.2014.1301si
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