A Mathematical Investigation of the Role of Intracranial Pressure Pulsations and Small Gradients in
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@Article{IJNAMB-3-36,
author = {KATHLEEN P. WILKIE, CORINA S. DRAPACA, AND SIVABAL SIVALOGANATHAN},
title = {A Mathematical Investigation of the Role of Intracranial Pressure Pulsations and Small Gradients in },
journal = {International Journal of Numerical Analysis Modeling Series B},
year = {2012},
volume = {3},
number = {1},
pages = {36--51},
abstract = {Cerebrospinal fluid (CSF) pulsations have been proposed as a possible causative mechanism for the ventricular enlargement that characterizes the neurological condition known as
hydrocephalus. This paper summarizes recent work by the authors to anaylze the effect of CSF
pulsations on brain tissue to determine if they are mechanically capable of enlarging the cerebral
ventricles. First a poroelastic model is presented to analyze the interactions that occur between
the fluid and porous solid constituents of brain tissue due to CSF pulsations. A viscoelastic model
is then presented to analyze the effects of the fluid pulsations on the solid brain tissue. The
combined results indicate that CSF pulsations in a healthy brain are incapable of causing tissue
damage and thus the ventricular enlargement observed in hydrocephalus. Therefore they cannot
be the primary cause of this condition. Finally, a hyper-viscoelastic model is presented and used
to demonstrate that small long-term transmantle pressure gradients may be a possible cause of
communicating hydrocephalus in infants.},
issn = {},
doi = {https://doi.org/},
url = {http://global-sci.org/intro/article_detail/ijnamb/269.html}
}
TY - JOUR
T1 - A Mathematical Investigation of the Role of Intracranial Pressure Pulsations and Small Gradients in
AU - KATHLEEN P. WILKIE, CORINA S. DRAPACA, AND SIVABAL SIVALOGANATHAN
JO - International Journal of Numerical Analysis Modeling Series B
VL - 1
SP - 36
EP - 51
PY - 2012
DA - 2012/03
SN - 3
DO - http://doi.org/
UR - https://global-sci.org/intro/article_detail/ijnamb/269.html
KW - Biomechanics
KW - Hydrocephalus
KW - Poroelasticity
KW - Viscoelasticity
KW - Fractional Calculus
AB - Cerebrospinal fluid (CSF) pulsations have been proposed as a possible causative mechanism for the ventricular enlargement that characterizes the neurological condition known as
hydrocephalus. This paper summarizes recent work by the authors to anaylze the effect of CSF
pulsations on brain tissue to determine if they are mechanically capable of enlarging the cerebral
ventricles. First a poroelastic model is presented to analyze the interactions that occur between
the fluid and porous solid constituents of brain tissue due to CSF pulsations. A viscoelastic model
is then presented to analyze the effects of the fluid pulsations on the solid brain tissue. The
combined results indicate that CSF pulsations in a healthy brain are incapable of causing tissue
damage and thus the ventricular enlargement observed in hydrocephalus. Therefore they cannot
be the primary cause of this condition. Finally, a hyper-viscoelastic model is presented and used
to demonstrate that small long-term transmantle pressure gradients may be a possible cause of
communicating hydrocephalus in infants.
KATHLEEN P. WILKIE, CORINA S. DRAPACA, AND SIVABAL SIVALOGANATHAN. (2012). A Mathematical Investigation of the Role of Intracranial Pressure Pulsations and Small Gradients in .
International Journal of Numerical Analysis Modeling Series B. 3 (1).
36-51.
doi:
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