TY - JOUR
T1 - Bioluminescence Tomography: Biomedical Background, Mathematical Theory, and Numerical Approximation
AU - Weimin Han & Ge Wang
JO - Journal of Computational Mathematics
VL - 3
SP - 324
EP - 335
PY - 2008
DA - 2008/06
SN - 26
DO - http://doi.org/
UR - https://global-sci.org/intro/article_detail/jcm/8628.html
KW - Biomedical imaging, Bioluminescence tomography (BLT), Inverse problem,
Regularization, Numerical approximation, Error analysis.
AB - <p style="text-align: justify;">Over the last couple of years molecular imaging has been rapidly developed to study physiological and pathological processes in vivo at the cellular and molecular levels. Among molecular imaging modalities, optical imaging stands out for its unique advantages, especially performance and cost-effectiveness. Bioluminescence tomography (BLT) is an emerging optical imaging mode with promising biomedical advantages. In this survey paper, we explain the biomedical significance of BLT, summarize theoretical results on the analysis and numerical solution of a diffusion based BLT model, and comment on a few extensions for the study of BLT.</p>