TY - JOUR
T1 - Recent Innovations in Silk Biomaterials
AU - Rangam Rajkhowa, Takuya Tsuzuki & Xun-Gai Wang
JO - Journal of Fiber Bioengineering and Informatics
VL - 4
SP - 202
EP - 213
PY - 2010
DA - 2010/02
SN - 2
DO - http://doi.org/10.3993/jfbi03201001
UR - https://global-sci.org/intro/article_detail/jfbi/5007.html
KW - Silk fibroin
KW - powder
KW - composite
KW - morphology
KW - application
AB - Silk contains a fibre forming protein, fibroin, which is biocompatible, particularly after removing the potentially 
immunogenic non-fibroin proteins. Silk can be engineered into a wide range of materials with diverse morphologies. 
Moreover, it is possible to regenerate fibroin with a desired amount of crystallinity, so that the biodegradation of silk 
materials can be controlled. These advantages have sparked new interest in the use of silk fibroin for biomedical 
applications, including tissue engineering scaffolds and carriers for sustained release of biologically active molecules. 
This article summarizes the current research related to the formation of silk materials with different morphologies, 
their biocompatibility, and examples of their biomedical applications. Recent work on the preparation of silk particles 
by mechanical milling and their applications in silk composite scaffolds is also discussed.