TY - JOUR
T1 - The Effect of Processing and Rheological Variables on the Morphology of Dermal Electrospun Scaffold
AU - Budimir Mijovic & Ante Agic
JO - Journal of Fiber Bioengineering and Informatics
VL - 4
SP - 181
EP - 186
PY - 2010
DA - 2010/03
SN - 3
DO - http://doi.org/10.3993/jfbi03201101
UR - https://global-sci.org/intro/article_detail/jfbi/4967.html
KW - Elecrospun processing
KW - dermal scaffold
KW - structural optimization
KW - rheological parameters
AB - The human skin is the largest organ which protects the body from disease and physical damage. When the skin has been seriously 
damaged through disease or burns, the body cannot act fast enough to produce necessary replacement cells. Artificial skin grafts 
were developed as a way to prevent such consequences. This work is related to the design of advanced dermal scaffolds 
(non-woven fibrous mats) to provide multifunctional properties. Defined target properties are attained by distributing specified 
base materials at multiple length scales ranging from several nanometers to millimeters. Tissue scaffolds were developed using 
the electrospinning process, which creates a non-woven fibrous construction of high permeability and proper mechanical integrity 
similar to the scale of the extra-cellular matrix of cells.