TY - JOUR T1 - Novel 2D Graphic Representation of Protein Sequence and Its Application JO - Journal of Fiber Bioengineering and Informatics VL - 1 SP - 23 EP - 33 PY - 2014 DA - 2014/07 SN - 7 DO - http://doi.org/10.3993/jfbi03201403 UR - https://global-sci.org/intro/article_detail/jfbi/4764.html KW - Graphic Representation KW - Protein Sequence KW - Sequence Similarity KW - Sub-cellular Location AB - In recent years, more and more researchers presented their graphic representations for protein sequence. Here, we present a new 2D graphic representation of protein sequence based on four physicochemical properties of 20 amino acids. By this graphic representation we define a distance calculation formula to quantificationally calculate the similarity degree of different protein sequences. Then we apply the proposed graphical curve and new distance in the similarity/dissimilarity comparison of 10 ND5 proteins and the protein sub-cellular localization prediction about two common test datasets, ZD98 and CL317. The results show the proposed method is easy and effective.