TY - JOUR
T1 - Synthesis and Characterization of Wool Keratin/Hydroxyapatite/Alginate Composites
AU - Zhu , Jing
AU - Li , Jiashen
JO - Journal of Fiber Bioengineering and Informatics
VL - 2
SP - 81
EP - 91
PY - 2019
DA - 2019/08
SN - 12
DO - http://doi.org/10.3993/jfbim00309
UR - https://global-sci.org/intro/article_detail/jfbi/13246.html
KW - Hydroxyapatite
KW - Wool keratin
KW - Alginate
KW - Nanocomposite
KW - Biomimetic
AB - <p>Interests in HA/polymer composites for bone tissue engineering have escalated due to their excellent
biological response to damaged tissues. HA/polymer composites have been researched as potential
implant in bone defects and voids. In this paper, HA was co-precipitated with two polymers including
wool keratin and alginate. By changing the concentrations of wool keratin solution, alginate solution
and Ca<sup>2+</sup> and PO<sup>3−</sup><sub>4&nbsp;</sub>solution, the ratios of inorganic and organic phase were changed. The final result
shows that HA embedded in the organic phase well and HA nanoparticles grown on the surface of wool
keratin and linear alginate macromolecules formed cross-linking around Ca<sup>2+</sup> of HA nanoparticles.</p>