TY - JOUR
T1 - Numerical Study on the Dynamics and Oxygen Uptake of Healthy and Malaria-Infected Red Blood Cells
AU - Jayathilake , P. G.
AU - Liu , Gang
AU - Tan , Zhijun
AU - Khoo , B. C.
JO - Advances in Applied Mathematics and Mechanics
VL - 5
SP - 549
EP - 568
PY - 2018
DA - 2018/05
SN - 7
DO - http://doi.org/10.4208/aamm.2014.m538
UR - https://global-sci.org/intro/article_detail/aamm/12063.html
KW - 
AB - <p style="text-align: justify;">Red blood cells (RBCs) are very important due to their role of oxygen transport
from lungs. As the malaria parasite grows in the malaria-infected red blood cells
(IRBCs), the properties of the cells change. In the present work, the oxygen uptake by
RBCs and IRBCs at the pulmonary capillaries is simulated using a numerical technique
based on the two-dimensional immersed interface method. The results for the oxygen
uptake by a stationary single RBC have fair agreements with the previously reported
results. The numerical results show that the malaria infection could significantly cause
deterioration on the oxygen uptake by red blood cells. The results also suggest that the
oxygen uptake by individual stationary RBC/IRBC would not be significantly affected
by the neighboring cells provided the separation distance is about the dimension
of the cell. Furthermore, it appears that the oxygen uptake by both RBCs and IRBCs is
dominated by mass diffusion over the convection although the Peclet number is of the
order of unity.</p>